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The Medical Therapy of Prostatic Symptoms (MTOPS) Trial was a double-blind, randomized, placebo-controlled, multicenter, 4- to 6-year research study (ordinary 5 years) in 3047 men regarding symptomatic BPH, that were randomized to get Proscar 5 mg/day (n=768), doxazosin 4 or 8 mg/day (n=756), the combo of Proscar 5 mg/day and also doxazosin 4 or 8 mg/day (n=786), or placebo (n=737).